产品说明
生化/生理作用
6-Methylflavone is a bitter taste blocker that significantly reduces bitter test of HIV drug tenofovir alafenamide in human subjects. 6-Methylflavone is a selective and potent modulator of TAS2R39 bitter test receptor that blocks it response to tenofovir alafenamide. 6-Methylflavone is a positive allosteric modulator (PAM) of α1β2γ2L and α1β2 GABAA receptors.
基本信息
经验(实验)分子式 | C16H12O2 |
分子量 | 236.27 |
MDL编号 | MFCD00017461 |
产品性质
质量水平 | 100 |
测定 | ≥98% (HPLC) |
形式 | powder |
颜色 | white to beige |
mp | 119-122 ℃ (dec.) (lit.) |
溶解性 | DMSO: 2 mg/mL, clear (warmed) |
储存温度 | 2-8℃ |
SMILES string | Cc1ccc2OC(=CC(=O)c2c1)c3ccccc3 |
安全信息
储存分类代码 | 11 - Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich