3,4′,5,7-Tetrahydroxyflavone 3-rhamnoside

产品名称：

482-39-3
Afzelin
Kaempferin
Kaempferol 3-rhamnoside
3,4′,5,7-Tetrahydroxyflavone 3-rhamnoside
Afzeloside
Kaempferol 3-O-alpha-L-rhamnoside

产品介绍：

产品说明

一般描述

Afzelin is a natural product derived from a plant source. Ficus palmata and Nymphaea odoratam are the major sources of afzelin, a flavonol glycoside.

应用

DNA-protective, antioxidant, anti-inflammatory, UV-absorbing and anti-bacterial activities. Afzelin has been used in HPLC (high performance liquid chromomatography) analysis of Comarum palustre L. extract to detect its major compounds.
DNA-protective, antioxidant, and anti-inflammatory, UV-absorbing activity, anti-bacterial activities.

生化/生理作用

NOS inhibitor, NADPH oxidase inhibitor, Afzelin is known to possess antibacterial, anti-inflammatory, anti-apoptotic and anti-tumor activities. Afzelin might serve as an effective treatment against P. aeruginosa related diseases. Afzelin also promotes apoptosis to inhibit cell proliferation in breast cancer. It exhibits anti-asthmatic effects in a mouse model.
iNOS inhibitor, NADPH oxidase inhibitor

基本信息

经验(实验)分子式	C₂₁H₂₀O₁₀
分子量	432.38
MDL编号	MFCD00210589
PubChem化学物质编号	329825042
NACRES	NA.25

产品性质

测定	≥90% (LC/MS-UV)
形式	solid
溶解性	DMSO: 1 mg/mL
储存温度	−20℃
SMILES string	OC1=CC(O)=C(C(C(O[C@H]2[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O2)=C(C3=CC=C(O)C=C3)O4)=O)C4=C1
InChI	1S/C21H20O10/c1-8-15(25)17(27)18(28)21(29-8)31-20-16(26)14-12(24)6-11(23)7-13(14)30-19(20)9-2-4-10(22)5-3-9/h2-8,15,17-18,21-25,27-28H,1H3/t8-,15-,17+,18+,21-/m0/s1
InChI key	SOSLMHZOJATCCP-AEIZVZFYSA-N

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable