产品说明
应用
Alanine racemase is used to convert L-alanine into D-alanine. Alanine racemase, from Sigma, has been used to isomerize L-[U-14C]alanine to a racemic mixture of L/D- [14C]alanine †.
生化/生理作用
Alanine racemase is involved in alanine, aspartate and D-alanine metabolism. 3-Fluoro-D-alanine and D-Cycloserine are known to inhibit alanine racemase.† Alanine racemase monomer is composed of two domains, an eight-stranded α/β barrel at the N-terminus and a C-terminal domain. The N-terminus includes residues 1-240, whereas the C-terminal comprises of the β-strand (residues 241-388). One molecule of pyridoxalphosphate (PLP) is present as the cofactor in each subunit.†
单位定义
One unit will convert 1.0 μmole of
外形
Aqueous solution containing 10 mM potassium phosphate
基本信息
| 酶学委员会(EC)编号 | 5.1.1.1 ( BRENDA | IUBMB ) |
| MDL编号 | MFCD03454300 |
| NACRES | NA.54 |
产品性质
| 质量水平 | 200 |
| 生物来源 | Bacillus sp. (B. stearothermophilus) |
| 形式 | buffered aqueous solution |
| specific activity | ≥10 IU/mg solid |
| 分子量 | Mr 78 kDa (2 subunits 39 kDa each) |
| 储存温度 | −20℃ |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
