产品说明
一般描述
Ang K1-3 is a single, non-glycosylated polypeptide chain containing 259 amino acids. It represents a proteolytic fragment of plasminogen containing the first three kringle structures. A specific inhibitor of endothelial cell growth and angiogenesis. Displays increased inhibitory activity (ED50 =70 nM) relative to kringles 1-4 (ED50 = 135 nM). Ang K1-3 reduces endothelial cell proliferation and acts as a potent inhibitor of angiogenesis and tumor growth.
外形
From 20 mM sodium acetate, pH 5.5, 4% mannitol
重悬
Centrifuge the vial prior to opening. Reconstitute in sterile distilled H?O or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml.
产品性质
生物来源 | human |
重组 | expressed in E. coli |
测定 | ≥95% (SDS-PAGE) |
形式 | lyophilized |
分子量 | 30.0 kDa |
包装 | pkg of 100 μg |
杂质 | Endotoxin, tested |
NCBI登记号 | P00747 |
运输 | wet ice |
储存温度 | −20℃ |
Gene Information | human ... PLG(5340) |
安全信息
储存分类代码 | 11 - Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich