Anti- CDKN1B/p27KIP1 antibody produced in rabbit

产品说明

一般描述

This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. Mutations in this gene are associated with multiple endocrine neoplasia type IV (MEN4).

免疫原

Recombinant protein of human CDKN1B/p27KIP1

外形

Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

产品性质

安全信息