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Anti-MLKL antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB5700092
包装型号
规格纯度
参考价格
4713.83 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-MLKL antibody produced in rabbit
Mlkl
hMLKL
产品介绍:

产品说明

一般描述

This gene belongs to the protein kinase superfamily. The encoded protein contains a protein kinase-like domain; however, is thought to be inactive because it lacks several residues required for activity. This protein plays a critical role in tumor necrosis factor (TNF)-induced necroptosis, a programmed cell death process, via interaction with receptor-interacting protein 3 (RIP3), which is a key signaling molecule in necroptosis pathway. Inhibitor studies and knockdown of this gene inhibited TNF-induced necrosis. High levels of this protein and RIP3 are associated with inflammatory bowel disease in children. Alternatively spliced transcript variants have been described for this gene.

免疫原

Recombinant protein of mouse MLKL

外形

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

储存及稳定性

Store at -20℃. Avoid freeze / thaw cycles.

产品性质

生物来源rabbit
质量水平100
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量 53
54
species reactivityrat, mouse, human
浓度0.68 mg/ml
technique(s)immunohistochemistry: 1:50-1:200
western blot: 1:500-1:2000
运输wet ice
储存温度−20℃
Gene Informationmouse ... MLKL(74568)

安全信息

储存分类代码12 - Non Combustible Liquids
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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