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Anti-PARP1 antibody produced in rabbit

品牌
Sigma-Aldrich
货号
AV33754
规格纯度
IgG fraction of antiserum
参考价格
5306.13 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-PARP1 antibody produced in rabbit
Anti-Poly(ADP-ribose) polymerase family, member 1
产品介绍:

产品说明

免疫原

Synthetic peptide directed towards the C terminal region of human PARP1

生化/生理作用

PARP1 encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. PARP1 can be cleaved resulting in fragements of 29 and 85 kDa.

序列

Synthetic peptide located within the following region: ISRLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVIDTSLLYN

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRESNA.41

产品性质

生物来源rabbit
质量水平100
偶联物unconjugated
抗体形式IgG fraction of antiserum
antibody product typeprimary antibodies
克隆polyclonal
分子量 113 kDa
species reactivitybovine, horse, mouse, human, dog, rabbit, rat, guinea pig
包装pkg of 100 μL buffered aqueous solution
pkg of 100 μg lyophilized powder
浓度0.5 mg - 1 mg/mL
technique(s)western blot: suitable
NCBI登记号NP_001609
UniProt登记号P09874
储存温度−20℃
Gene Informationhuman ... PARP1(142)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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