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Anti-ABCA1 Antibody, clone AB.H10

品牌
Sigma-Aldrich
货号
MAB10005
规格纯度
clone AB.H10, Chemicon®, from mouse
参考价格
6538.49 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-ABCA1 Antibody, clone AB.H10
ATP-binding cassette transporter 1, ABC-1, Cholesterol efflux regulatory protein
产品介绍:

产品说明

一般描述

Mutations in the ABCA1 gene are associated with Tangier disease (TD). TD is an autosomal recessive disorder results from an absence of plasma HDL, cholesterol ester depositing in the reticulo-endothelial system and disorders in cellular lipid trafficking. It is expressed on the plasma membrane and the Golgi complex, and is regulated by cholesterol flux. Regulation of the cholesterol flux between HDL and macrophages is competitive between ABCA1 and SR-BI.

特异性

Recognize specifically ABCA1 from human, mouse, and chicken.

免疫原

Recombinant fragment, corresponding to amino acids 1800-2260 of Human ABCA1.

应用

Research Category
Metabolism
Research Sub Category
Lipid Metabolism & Weight Regulation
This Anti-ABCA1 Antibody, clone AB.H10 is validated for use in ELISA, IP, WB, IH(P) for the detection of ABCA1.
ELISA
Immunohistochemistry (Paraffin): 5 μg/mL. Perform heat mediated antigen retrieval in sodium citrate buffer (pH 6), before commencing with IHC staining protocol. Amplification with biotin-streptavidin may be required.
Immunoprecipitation
Western Blot: 1 μg/mL. Predicted molecular weight: 254 kDa.

Optimal working dilutions must be determined by end user.

外形

Format: Purified
Presented as a liquid in PBS, pH 7.4 with 0.05% sodium azide.

储存及稳定性

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. Aliquot will be stable at 4°C for 3 months.

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法律信息

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss32160702
NACRESNA.41

产品性质

质量水平100
生物来源mouse
抗体形式purified antibody
antibody product typeprimary antibodies
克隆AB.H10, monoclonal
species reactivityhuman, mouse, chicken
manufacturer/tradenameChemicon®
technique(s)ELISA: suitable
immunohistochemistry: suitable (paraffin)
immunoprecipitation (IP): suitable
western blot: suitable
同位素/亚型IgG1
NCBI登记号NM_005502.2
UniProt登记号O95477
运输dry ice
Gene Informationhuman ... ABCA1(19)

安全信息

储存分类代码10 - Combustible liquids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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