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Anti-ADNP1 Antibody, clone 5F5.1

品牌
Sigma-Aldrich
货号
MABN677
规格纯度
clone 5F5.1, from mouse
参考价格
5520.38 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-ADNP1 Antibody, clone 5F5.1
产品介绍:

产品说明

一般描述

ADNP1, also known as Activity-dependent neuroprotector homeobox protein, and encoded by the gene ADNP/ADNP1/KIAA0784, is a potential transcription factor that appears to mediate some of the neuroprotective peptide VIP associated effects involving normal growth and cancer proliferation. ADNP1 is widely expressed and localized to the nucleus. ADNP1 is strongly expressed in heart and skeletal muscle tissue and the brain. ADNP1 is also found expressed in colon and breast cancer tissues but not in normal tissues, thus ADNP1 can be used as a potential cancer marker in some tissues. ADNP1 is upregulated in normal proliferative tissues by VIP, and it may increase the viability of certain cell types through the modulation of p53 activity. Interestingly, new research shows that ADNP1 may be a potential biomarker for Alzheimer’s disease, where ADP1 expression was specifically down-regulated in AD patients.

免疫原

Epitope: Near C-terminus
GST-tagged recombinant protein corresponding to human ADNP1, near the C-terminus.

应用

This Anti-ADNP1 Antibody, clone 5F5.1 is validated for use in Western Blotting for the detection of ADNP1.
Research Category
Neuroscience
Research Sub Category
Developmental Signaling

质量

Evaluated by Western Blotting in SH-SY-5Y cell lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected ADNP1 in 200 µg of SH-SY-5Y cell lysate.

目标描述

~145 kDa observed

外形

Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Format: Purified
Protein G Purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

其他说明

Concentration: Please refer to lot specific datasheet.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss32160702
NACRESNA.41

产品性质

质量水平100
生物来源mouse
抗体形式purified immunoglobulin
antibody product typeprimary antibodies
克隆5F5.1, monoclonal
species reactivityhuman
technique(s)western blot: suitable
同位素/亚型IgG1κ
NCBI登记号NP_056154
UniProt登记号Q9H2P0
运输wet ice
Gene Informationhuman ... ADNP(23394)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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