产品说明
一般描述
Anterior gradient protein 2 homolog (AGR2) (also known as secreted cement gland protein XAG-2 homolog) is thought to be a metastasis-inducing protein in breast cancer models and may be used as a means of detecting the outcome of hormonally treated patients with breast cancer. AGR2 may also play an important role in intestinal mucus production. Recent researched has also linked AGR2 to metastasis. Lower levels of AGR expression in prostate cancer may be highly predictive of the reoccurrence of disease even after a prostatectomy.
免疫原
KLH-conjugated linear peptide corresponding to human AGR2.
应用
Research Category
Cell Structure
Detect AGR2 using this Anti-AGR2 Antibody, clone 5G1.1 validated for use in western blotting & IHC.
Research Sub Category
ECM Proteins
Immunohistochemistry Analysis: A 1:2,000 dilution from a representative lot detected AGR2 in human stomach and human ileum tissue.
质量
Evaluated by Western Blotting in COLO-201 cell lysate.
Western Blotting Analysis: 0.5 µg/mL of this antibody detected AGR2 in 10 µg of COLO-201 cell lysate.
目标描述
~18 kDa observed
外形
Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Format: Purified
Protein G Purified
储存及稳定性
Stable for 1 year at 2-8°C from date of receipt.
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
产品性质
质量水平 | 100 |
生物来源 | mouse |
抗体形式 | purified immunoglobulin |
antibody product type | primary antibodies |
克隆 | 5G1.1, monoclonal |
species reactivity | human |
technique(s) | immunohistochemistry: suitable western blot: suitable |
同位素/亚型 | IgG1κ |
NCBI登记号 | NP_006399 |
UniProt登记号 | O95994 |
运输 | wet ice |
Gene Information | human ... AGR2(10551) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich