产品说明
一般描述
Activity-regulated cytoskeleton-associated protein (ARC), also known as Activity-regulated gene 3.1 protein homolog (ARG3.1), plays an important role in synaptic plasticity and the formation of long-term memory. ARC is enriched in the postsynaptic density of dendritic spines and regulates endocytosis of AMPA receptors in response to synaptic activity and is required for homeostatic synaptic scaling of AMPA receptors. ARC also plays a role in the regulation of cell morphology, cytoskeletal organization, stress fiber dynamics, and cell migration.
免疫原
GST-tagged recombinant protein corresponding to human ARC.
应用
Anti-ARC Antibody, clone 6F9.1 is a highly specific mouse monoclonal antibody, that targets ARC & has been tested in western blotting & IHC (Paraffin).
Research Sub Category
Apoptosis - Additional
Immunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected ARC in human brain tissue.
Research Category
Apoptosis & Cancer
质量
Evaluated by Western Blotting in human hippocampus tissue lysate.
Western Blotting Analysis: 0.2 µg/mL of this antibody detected ARC in 200 µg of human hippocampus tissue lysate.
目标描述
~ 45 kDa observed
外形
Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Format: Purified
Protein G Purified
储存及稳定性
Stable for 1 year at 2-8°C from date of receipt.
分析说明
Control
Human hippocampus tissue lysate
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
产品性质
质量水平 | 100 |
生物来源 | mouse |
抗体形式 | purified immunoglobulin |
antibody product type | primary antibodies |
克隆 | 6F9.1, monoclonal |
species reactivity | human |
technique(s) | immunohistochemistry: suitable (paraffin) western blot: suitable |
同位素/亚型 | IgG1κ |
NCBI登记号 | NP_056008 |
UniProt登记号 | Q7LC44 |
运输 | wet ice |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich