Anti-ATG5 Antibody, clone 177.19

产品说明

一般描述

ATG5 is required for autophagy. It conjugates to ATG12 and associates with isolation membrane to form autophagosomes. The conjugate detaches from the membrane immediately before or after autophagosome formation is completed. Conjugation to ATG12 is essential for autophagy, but is not required for association with isolation membrane. ATG5 also plays an important role in the apoptotic process. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity

特异性

The antibody reacts with the 50 kDa ATG5 protein.
Other species have not been tested.

免疫原

Linear Peptide, aa: 8-318

应用

Research Sub Category
Apoptosis - Additional
This Anti-ATG5 Antibody, clone 177.19 is validated for use in WB, IP for the detection of ATG5.
Immunoprecipitation: HeLa cell lysate
Research Category
Apoptosis & Cancer

质量

Western Blot Analysis: 0.5 ug/mL of this antibody detected ATG5 on HeLa cell lysate.

目标描述

50 kDa

联系

Replaces: MABC137

外形

Purified in 0.1M Tris-Glycine (pH7.4) 150mM NaCl with 0.05% NaN3.
Format: Purified
Protein G Purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

分析说明

Control
Western Blot and Immunoprecipitation: HeLa cell lysate.

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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