产品说明
一般描述
Monoclonal Anti-β-Tubulin I (mouse IgG1 isotype) is derived from the SAP.4G5 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from a BALB/c mouse. Tubulin is the major building block of microtubules, an intracellular cylindrical filamentous structure, that is present in almost all eukaryotic cells. Tubulin exists in all cells as a 100 kDa protein, which assembles from heterodimers of α-tubulin and β-tubulin; both have a molecular weight of 55 kDa and share considerable homology.
免疫原
synthetic peptide corresponding to the C-terminal sequence of ß-tubulin isotype I, conjugated to BSA
应用
Anti-β-Tubulin I antibody, Mouse monoclonal has been used in:
生化/生理作用
β-Tubulin I is also useful in deducing the role that different tubulin isotypes play in nerve development, function or maintenance.
外形
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
产品性质
生物来源 | mouse |
抗体形式 | purified from hybridoma cell culture |
antibody product type | primary antibodies |
克隆 | SAP.4G5, monoclonal |
形式 | buffered aqueous solution |
分子量 | ~55 kDa |
species reactivity | chicken, Xenopus, gerbil, bovine, monkey, mouse, hamster, human, rat, canine |
浓度 | ~1.0 mg/mL |
technique(s) | immunoblotting: 0.06-0.12 μg/mL using HeLa cell extract immunofluorescence: 1-2.5 μg/mL using HeLa cells immunohistochemistry: 1-2 μg/mL using heat-retrieved formalin-fixed, paraffin-embedded human fallopian tube or testis sections. |
同位素/亚型 | IgG1 |
UniProt登记号 | P07437 |
运输 | dry ice |
储存温度 | −20℃ |
Gene Information | human ... TUBB(203068) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich