Anti-BACE2 (ab1) antibody produced in rabbit

产品说明

一般描述

β-site amyloid precursor protein- cleaving enzyme 2 (BACE2) is a glycoprotein which is part of the transmembrane aspartic protease family. The gene encoding this protein is localized on human chromosome 21q22.3.

免疫原

a synthetic peptide corresponding to amino acids 44-59 of human BACE2.

生化/生理作用

β-site amyloid precursor protein- cleaving enzyme 2 (BACE2) has a role in the non-amyloidogenic processing of amyloid precursor protein. It also possesses an amyloid β-degrading protease activity. Cells of individuals with Down′s syndrome show an enhanced expression of BACE1 mRNA and the protein.

联系

The action of this antibody can be blocked using blocking peptide SBP2247.

外形

Solution in phosphate buffered saline containing 0.02% sodium azide

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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