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Anti-BLZF1 antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB4503415
规格纯度
affinity isolated antibody
参考价格
5045.46 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-BLZF1 antibody produced in rabbit
Basic leucine zipper nuclear factor 1
JEM-1
p45 basic leucine-zipper nuclear factor
产品介绍:

产品说明

一般描述

Anti-BLZF1 Antibody detects endogenous levels of total BLZF1 protein.
The gene BLZF1 (basic leucine zipper nuclear factor 1) is mapped to human chromosome 1q24. It belongs to the b-ZIP family of proteins. The encoded protein has a PEST (proline [P], glutamic acid [E], serine [S], and threonine [T]) motif, a putative leucine repeat and several phosphorylation sites. This protein is present in the nucleus, cytoplasm and Golgi apparatus.

免疫原

The antiserum was produced against synthesized peptide derived from human BLZF1.

Immunogen Range: 10-59

生化/生理作用

BLZF1 (basic leucine zipper nuclear factor 1) might work as a transcription factor. It is involved in epigenetic regulation by binding to DNMT3L (DNA methyltransferase 3 like) and also participates in Wnt/β-catenin signaling. The BLZF1 gene is downregulated in acute promyelocytic leukemia (APL) cell line NB4. On the other hand, it is upregulated in presence of dengue virus infection. BLZF1 also interacts with GRASP55 (the medial-Golgi matrix protein) and the GTP form of rab2. It is involved in the secretory protein transport and maintenance of the Golgi structure. This gene is downregulated in hepatocellular carcinoma. This low expression is associated with poor overall survival.

特点和优势

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外形

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

基本信息

NACRESNA.41

产品性质

生物来源rabbit
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量antigen 44 kDa
species reactivityhuman, mouse
浓度~1 mg/mL
technique(s)ELISA: 1:20000
western blot: 1:500-1:1000
NCBI登记号Q9H2G9
UniProt登记号Q9H2G9
运输wet ice
储存温度−20℃
Gene Informationhuman ... BLZF1(8548)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKnwg
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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