产品说明
一般描述
Bone morphogenetic protein 15 (BMP15), also known as Growth/differentiation factor 9B (GDF9B), is part of the transforming growth factor-beta (TGF-β) superfamily. BMP15 is an oocyte-specific growth and differentiation factor that stimulates folliculogenesis and development as well as granulosa cell (GC) growth. BMP15 is expressed exclusively in the oocyte. BMP15 defects are linked to ovarian dysgenesis type 2 (ODG2) and premature ovarian failure type 4 (POF4). Potentially, BMP15 could be an oogenesis marker, used to monitor the differentiation of human amniotic fluid stem cells into oocyte-like cells.
免疫原
KLH-conjugated linear peptide corresponding to human BMP15.
应用
Anti-BMP Antibody15 is a highly specific rabbit polyclonal antibody, that targets BMP & has been tested in western blotting & ICC.
Research Sub Category
Pluripotent & Early Differentiation
Research Category
Stem Cell Research
Immunocytochemistry Analysis: 2.5 µg/mL from a representative lot detected BMP15 in NIH/3T3 cells.
质量
Evaluated by Western Blotting in NIH/3T3 cell lysate.
Western Blotting Analysis: 1 µg/mL of this antibody detected BMP15 in 15 µg of NIH/3T3 cell lysate.
目标描述
~53 kDa observed. Uncharacterized bands may appear in some lysate(s).
外形
Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
Antigen Affinity Purified
储存及稳定性
Stable for 1 year at 2-8°C from date of receipt.
分析说明
Control
NIH/3T3 cell lysate
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
产品性质
生物来源 | rabbit |
质量水平 | 100 |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
纯化方式 | affinity chromatography |
species reactivity | mouse |
species reactivity (predicted by homology) | human (immunogen homology) |
technique(s) | immunocytochemistry: suitable western blot: suitable |
UniProt登记号 | O95972 |
运输 | wet ice |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 2 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich