产品说明
一般描述
Bonzo Antibody: Human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) require coreceptors, in addition to CD4, to infect target cells. Some G protein-coupled receptors including CCR5, CXCR4, CCR3, and CCR2b in the chemokine receptor family have been identified as HIV coreceptors. An orphan G protein-coupled receptor was recently cloned and designated Bonzo, STRL33 and TYMSTR, and identified as HIV and SIV coreceptor. Bonzo/STRL33 is used by SIV, HIV-2 and HIV-1. The messenger RNA of Bonzo/STRL33 is expressed in lymphoid tissues and activated peripheral blood lymphocytes.
免疫原
Bonzo antibody was raised against a 20 amino acid peptide near the carboxy terminus of human Bonzo.The immunogen is located within the last 50 amino acids of Bonzo.
应用
Bonzo antibody can be used for detection of Bonzo by Western blot at 1:1000 dilution. Antibody validated: Western Blot in human samples. All other applications and species not yet tested.
外形
Supplied in PBS containing 0.02% sodium azide.
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | purified antibody (DEAE) |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | liquid |
| species reactivity | human |
| 浓度 | 1 mg/mL |
| technique(s) | western blot: suitable |
| 同位素/亚型 | IgG |
| UniProt登记号 | O00574 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... CXCR6(10663) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | nwg |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
