Anti-CASPASE-12 (ab1) antibody produced in rabbit

产品说明

一般描述

Caspase 12 (CASP12), a member of the caspase family, is expressed in the Golgi complex.

免疫原

a peptide corresponding to amino acids 2-17 of murine caspase-12.

应用

Anti-CASPASE-12 (ab1) antibody produced in rabbit has been used in western blotting.

生化/生理作用

Murine caspase 12 (CASP12) is activated during endoplasmic reticulum stress and activates other caspases which act on substrates, ultimately leading to apoptosis. The protein has been shown to be activated during progression of retinal degeneration in animal models. In mice models, CASP12 has been shown to cause neuronal death resulting from ischemia/reperfusion.

联系

The action of this antibody can be blocked using blocking peptide SBP2325.

外形

Solution in phosphate buffered saline containing 0.02% sodium azide

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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