产品说明
一般描述
Caveolin 2 (CAV2) gene with three exons is mapped to human chromosome 7q31. The encoded protein is expressed in variety of human tissues, including the scleral spur cells, trabecular meshwork and retinal ganglion cells of the eye.
免疫原
Synthetic peptide directed towards the N terminal region of human CAV2
生化/生理作用
Caveolin 2 (CAV2) along with CAV1, participates in transcytosis by inducing the formation of specialized invaginations of the plasma membrane called caveolae. CAV2 might be involved in the process of hormonal translocation. It is also implicated in the regulation of cancer progression. CAV2 plays an essential role in the regulation of sex hormone 17β-estradiol (E2)-dependent cellular proliferation. Genetic variation in the gene is associated with the increased risk of developing primary open-angle glaucoma (POAG).
序列
Synthetic peptide located within the following region: LVIPYNEKPEKPAKTQKTSLDEALQWRDSLDKLLQNNYGLASFKSFLKSE
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| MDL编号 | MFCD01633098 |
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | 18 kDa |
| species reactivity | guinea pig, rat, rabbit, dog, human, bovine, mouse, horse, sheep |
| 浓度 | 0.5 mg - 1 mg/mL |
| technique(s) | immunohistochemistry: suitable western blot: suitable |
| UniProt登记号 | P51636 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... CAV2(858) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
