产品说明
一般描述
Anti-CD18 Antibody detects endogenous levels of total CD18 protein.
CD18/ ITGB2 (integrin subunit β2) is also termed as Mac-1 or complement receptor 3. The ITGB2 gene is mapped to human chromosome 21q22.3. It is mainly expressed in blood. Anti-CD18 Antibody detects endogenous levels of total CD18 protein.
免疫原
The antiserum was produced against synthesized peptide derived from human CD18/ITGB2.
Immunogen Range: 720-769
生化/生理作用
CD18/ ITGB2 (integrin subunit β 2) plays an important role in the progression and function of T-cells. Mutations in ITGB2 results in leukocyte adhesion deficiency type 1, which has an established role in T-cell development and function. ITGB2/CD18 is associated with chronic colitis.
特点和优势
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外形
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
产品性质
| 生物来源 | rabbit |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | antigen 84 kDa |
| species reactivity | rat, human, mouse |
| 浓度 | ~1 mg/mL |
| technique(s) | ELISA: 1:1000 immunofluorescence: 1:100-1:500 |
| NCBI登记号 | P05107 |
| UniProt登记号 | P05107 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... ITGB2(3689) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | nwg |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
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