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Anti-CD3 antibody, Rabbit monoclonal

品牌
Sigma-Aldrich
货号
SAB5500057
规格纯度
clone SP162, recombinant, expressed in proprietary host, affinity isolated antibody
参考价格
4906.25 *本价格含增值税费
促销
服务
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  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-CD3 antibody, Rabbit monoclonal
产品介绍:

产品说明

一般描述

CD3E (CD3e molecule) gene is mapped to human chromosome 11q23.3. This gene encodes fora subunit of T-cell regulator (TCR) protein complex. It possesses IgG (immunoglobulin G)-like extracelluar domain at the N-terminal, a transmembrane domain, a peptide bridge and an immunoreceptor tyrosine-based activation motif (ITAM) towards the cytoplasm. The protein also contains basic residue-rich sequence (BRS).
This antibody reacts with the intracytoplasmic portion of the CD3 antigen expressed by T cells. It stains human T cells in both the cortex and medulla of the thymus and in peripheral lymphoid tissues. This antibody is suitable for staining normal and neoplastic T cells in formalin-fixed, paraffin-embedded tissues.

免疫原

Synthetic peptide corresponding to internal region of the epsilon chain of human CD3 protein.

应用

Anti-CD3 antibody, Rabbit monoclonal has been used in immunohistochemistry.

生化/生理作用

CD3E (CD3e molecule) gene is associated with actin cytoskeletal rearrangement, through activation of a number of signaling pathways. CD3E is essential for membrane binding of T-cell regulator (TCR) protein complex.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外形

0.1 ml rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRESNA.41

产品性质

生物来源rabbit
质量水平100
重组expressed in proprietary host
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆SP162, monoclonal
species reactivityhuman (tested)
species reactivity (predicted by homology)chicken, rabbit, dog, bovine, rat, mouse, pig
technique(s)flow cytometry: 1:150
immunoblotting: 1:150
immunohistochemistry: 1:150
同位素/亚型IgG
UniProt登记号P07766
运输wet ice
储存温度2-8℃
Gene Informationhuman ... CD3E(916)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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