产品说明
一般描述
The A20 antibody reacts with mouse CD45.1, also known as Ly5.1, which is a strain-specific allelic form of the CD45 Leukocyte Common Antigen (LCA). Functionally, CD45 is a protein tyrosine phosphatase whose broad cell distribution supports a critical role in many leukocyte functions, including regulation of signal transduction and cell activation associated with the T cell and B cell receptors. The A20 antibody is typically used as a leukocyte marker in Ly5.1 mouse strains: SJL/J, DA, STS/A and RIII. The antibody has been demonstrated to specific for CD45.1 and is not cross-reactive with CD45.2 bearing cells.
免疫原
Immunogen information for this antibody is proprietary information.
应用
This mouse monoclonal antibody Anti-CD45.1 (mouse), APC, clone A20 validated for use in IP, IHC & Flow Cytometry for the detection of CD45.1.
Research Category
Inflammation & Immunology
质量
The monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation.
Flow Cytometry Analysis: 0.5 μg of this antibody detected CD45.1 in one million C57Bl/6 or SJL splenocytes.
外形
Size Exclusion Chromatography
Purified Mouse Monoclonal Antibody in buffer containing 10 mM NaH2PO4, 150 mM NaCl, 0.1% gelatin, pH 7.2, and up to 0.1% sodium azide.
储存及稳定性
It is recommended to store the product undiluted at 2-8°C and protected from prolonged exposure to light. Do not freeze.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
产品性质
质量水平 | 100 |
生物来源 | mouse |
偶联物 | Allophycocyanin conjugate |
抗体形式 | purified antibody |
antibody product type | primary antibodies |
克隆 | A20, monoclonal |
species reactivity | mouse |
浓度 | 0.2 mg/mL |
technique(s) | flow cytometry: suitable immunohistochemistry: suitable immunoprecipitation (IP): suitable |
同位素/亚型 | IgG2aκ |
UniProt登记号 | P06800 |
运输 | wet ice |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | nwg |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich