产品说明
特异性
This antibody is specific to the integrin alpha6 chain which is expressed on epithelial and endothelial basement membrane. The VLA alpha6 chain, which consists of a single disulphide linked 120 kDa subunit and a small doublet subunit of 25/30 kDa, is non covalently associated with the VLA beta-chain (CD29) in VLA-6 or alpha6/beta1 complex or with integrin beta4 chain (alpha6/beta4).
The antigen is also expressed on platelets, monocytes, thymocytes and T lymphocytes.
FUSION PARTNER: NS1 myeloma cell line
免疫原
Cell line SW/222 (Human colorectal carcinoma)
应用
Research Category
Cell Structure
Research Sub Category
Integrins
This Anti-CD49f Antibody, clone 4F10 is validated for use in FC, IP, IH for the detection of CD49f.
Immunohistological studies on frozen sections
Immunoprecipitation of the laminin receptor
Flow Cytometry
Optimal working dilutions must be determined by the end user.
联系
Replaces: MAB2254
外形
The monoclonal was purified by protein A affinity chromatography and is presented as a liquid in phosphate buffered saline containing 10mM sodium azide and 1 mg/mL bovine serum albumin.
Format: Purified
储存及稳定性
Store an 2-8°C for up to 12 months from date of receipt. For long term storage aliquot antibody into small volumes and store at -20°C. Avoid repeated freeze-thaw cycles.
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
产品性质
质量水平 | 100 |
生物来源 | mouse |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | 4F10, monoclonal |
species reactivity | human |
manufacturer/tradename | Chemicon® |
technique(s) | flow cytometry: suitable immunohistochemistry: suitable immunoprecipitation (IP): suitable |
同位素/亚型 | IgG2b |
NCBI登记号 | NM_000210.2 NM_001079818.1 |
UniProt登记号 | P23229 |
运输 | wet ice |
Gene Information | human ... ITGA6(3655) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 2 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich