Anti-CDT1 antibody produced in rabbit

产品说明

一般描述

Chromatin licensing and DNA replication factor 1/Cdc10-dependent transcript 1 (CDT1), a G1-specific cell-cycle factor, belongs to the pre-replication complex (pre-RC). The CDT1 gene is located on the human chromosome 16q24.3.

免疫原

Synthetic peptide containing a sequence corresponding to a region within amino acids 448 and 490 (Q9H211) of CDT1 according to AAH08676

应用

Suggested starting dilutions are as follows: ICC/IF: 1:100-1:1000, IHC-P: 1:100-1:1000, WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.

生化/生理作用

Chromatin licensing and DNA replication factor 1/Cdc10-dependent transcript 1 (CDT1) is involved in minichromosome maintenance (MCM) loading at the G1 phase of the cell cycle. It plays a key role in origin licensing in eukaryotic cells. It is a DNA replication protein that stimulates the production of pre-replicative complexes and replication in the next cell cycle by accumulating at the end of the cell cycle. The CDT1 gene mutation can cause Meier–Gorlin syndrome, a type of primordial dwarfism.

特点和优势

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外形

1XPBS, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

产品性质

安全信息

象形图
警示用语：	Warning
危险声明	H317 - H412
预防措施声明	P261 - P272 - P273 - P280 - P302 + P352 - P333 + P313
危险分类	Aquatic Chronic 3 - Skin Sens. 1
储存分类代码	12 - Non Combustible Liquids
WGK	WGK 2