产品说明
一般描述
Chromodomain-helicase-DNA-binding protein 1 (CHD1) is an ATP-dependent chromatin-remodeling factor. The CHD family of proteins contains two domains : chromo (chromatin organization modifier) and SNF2-related helicase/adenosine triphosphatase (ATPase).
免疫原
synthetic peptide corresponding to the C-terminal region of human CHD1 , conjugated to KLH.
应用
Anti-CHD1 (C-terminal) antibody from rabbit has been used in immunoblotting and immunofluorescence.
生化/生理作用
Chromodomain-helicase-DNA-binding protein 1 (CHD1) modifies chromatin structure affecting the interaction of transcriptional apparatus to its chromosomal DNA template. CHD1 is required for maintaining open chromatin and pluripotency in embryonic stem cells (ESCs).
外形
a solution in 0.01 M phosphate buffered saline pH 7.4, containing 15 mM sodium azide
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
产品性质
| 生物来源 | rabbit |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 形式 | buffered aqueous solution |
| species reactivity | mouse, human |
| 浓度 | ~1.0 mg/mL |
| technique(s) | immunoblotting: 2.5-5.0 μg/mL using whole extracts of mouse P19 cells. immunofluorescence: 2.5-5.0 μg/mL using human HeLa cells. |
| UniProt登记号 | O14646 |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| Gene Information | human ... CHD1(1105) mouse ... Chd1(12648) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
