产品说明
一般描述
CHRNA5 codes for a subunit of the nicotinic acetylcholine receptor. Variations in this gene have been linked to the risk of nicotine and alcohol dependence, as well as lung cancer.
Rabbit Anti-CHRNA5 antibody recognizes zebrafish, canine, bovine, mouse, chicken, rat, and human CHRNA5.
免疫原
Synthetic peptide directed towards the middle region of human CHRNA5
应用
Rabbit Anti-CHRNA5 antibody is suitable for western blot applications at a concentration of 1 μg/ml.
生化/生理作用
Nicotinic acetylcholine receptors (nAChRs), such as CHRNA5, are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The nAChRs are thought to be (hetero)pentamers composed of homologous subunits.
序列
Synthetic peptide located within the following region: DGSQVDIILEDQDVDKRDFFDNGEWEIVSATGSKGNRTDSCCWYPYVTYS
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | 53 kDa |
| species reactivity | human, horse, bovine, guinea pig, dog, rat, mouse |
| 浓度 | 0.5 mg - 1 mg/mL |
| technique(s) | western blot: suitable |
| NCBI登记号 | NP_000736 |
| UniProt登记号 | P30532 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... CHRNA5(1138) |
安全信息
| 储存分类代码 | 10 - Combustible liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
