产品说明
一般描述
Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules. Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2. This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle.
免疫原
CLASP2 (NP_055912, )
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human CLASP2.
外形
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
基本信息
NACRES | NA.41 |
产品性质
生物来源 | rabbit |
偶联物 | unconjugated |
抗体形式 | IgG fraction of antiserum |
antibody product type | primary antibodies |
克隆 | polyclonal |
形式 | buffered aqueous solution |
species reactivity | human |
technique(s) | immunohistochemistry: 1:50-1:100 indirect ELISA: 1:1000 |
NCBI登记号 | NP_055912 |
UniProt登记号 | O75122 |
运输 | dry ice |
储存温度 | −20℃ |
Gene Information | human ... CLASP2(23122) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | nwg |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich