Anti-Claudin-11 Antibody

产品说明

一般描述

Claudin-11 (CLDN11; or Oligodendrocyte-specific protein) is expressed in Sertoli cells of the testis. It is involved in the formation of tight junctions, which is required for spermatogenesis. Previous studies have indicated that claudin-11 may prevent the progression of bladder cancer by blocking cell invasion and metastatis.

特异性

This antibody recognizes the cytoplasmic domain of Claudin-11.
Other homologies: Mouse and Rat (93% sequence homology).

免疫原

KLH-conjugated linear peptide corresponding to the cytoplasmic domain of human Claudin-11.
Epitope: Cytoplasmic domain

应用

Research Category
Cell Structure
Western Blot Analysis: 1 µg/mL from a representative lot detected Claudin-11 in human kidney tissue lysate.

Western Blot Analysis: 2 µg/mL from a representative lot detected Claudin-11 in human testis tissue lysate.
Anti-Claudin-11 Antibody is an antibody against Claudin-11 for use in Western Blotting.
Research Sub Category
ECM Proteins

质量

Evaluated by Western Blot in human brain tissue lysate.

Western Blot Analysis: 0.5 µg/mL of this antibody detected Claudin-11 in 10 µg of human brain tissue lysate.

目标描述

~22 kDa observed. An uncharacterized band may be observed at ~60 kDa in some tissue lysates.

外形

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Affinity purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

分析说明

Control
Human brain tissue lysate

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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