产品说明
一般描述
Claudin 1 (CLDN1) is a component of tight junctions. It is part of the transmembrane tight junction protein family. The CLDN1 gene is localized on human chromosome 3q28.
免疫原
CLDN1 antibody was raised against a 20 amino acid peptide near the carboxyl terminus of human CLDN1.
生化/生理作用
Claudin 1 (CLDN1) has a role in epithelial-mesenchymal transition. It is a sealing and tightening junctional protein. CLDN1 has been shown to be downregulated in lung adenocarcinoma. Mutations in this gene have also been linked to neonatal ichthyosis and sclerosing cholangitis.
特点和优势
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
联系
The action of this antibody can be blocked using blocking peptide SBP3500438.
外形
Supplied in PBS with 0.02% sodium azide.
基本信息
| MDL编号 | MFCD02096101 |
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| species reactivity | mouse, rat, human |
| technique(s) | immunocytochemistry: suitable immunofluorescence: suitable indirect ELISA: suitable western blot: suitable |
| NCBI登记号 | CAG33419 |
| UniProt登记号 | O95832 |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| Gene Information | human ... CLDN1(9076) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
