产品说明
一般描述
Anti-Collagen XII α1 Antibody detects endogenous levels of total Collagen XII α1 protein.
Collagen XII α1 belongs to the FACIT collagens (fibril-associated collagens with interrupted triple helices) family. It codes for the alpha chain of type XII collagen. It is located on human chromosome 6q13.
免疫原
The antiserum was produced against synthesized peptide derived from human Collagen XII alpha1.
Immunogen Range: 1481-1530
应用
Anti-Collagen XII α1 antibody has been used in immunohistochemistry.
生化/生理作用
Collagen XII α1 participates in a benign bone tumor, subungual exostosis. Collagen XII organize the collagen fibrils and thereby preserves the bone and muscle integrity. Mutations in collagen XII results in Ehlers–Danlos/myopathy overlap syndrome.
特点和优势
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外形
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
NACRES | NA.41 |
产品性质
生物来源 | rabbit |
质量水平 | 100 |
偶联物 | unconjugated |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
形式 | buffered aqueous solution |
分子量 | antigen 333 kDa |
species reactivity | human |
浓度 | ~1 mg/mL |
technique(s) | ELISA: 1:1000 immunofluorescence: 1:100-1:500 immunohistochemistry: 1:50-1:100 |
NCBI登记号 | Q99715 |
UniProt登记号 | Q99715 |
运输 | wet ice |
储存温度 | −20℃ |
Gene Information | human ... COL12A1(1303) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | nwg |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich