产品说明
一般描述
Anti-CYB5R3 Antibody detects endogenous levels of total CYB5R3 protein.
CYB5R3 (cytochrome b5 reductase 3) codes for a membrane bound form of cytochrome b5 reductase. It is present in plasma membranes. It is mapped to human chromosome 22q13.2.
免疫原
The antiserum was produced against synthesized peptide derived from human CYB5R3.
Immunogen Range: 137-186
生化/生理作用
CYB5R3 (cytochrome b5 reductase 3) regulates connecting aerobic metabolism and aging processes.This protein is involved in cholesterol biosynthesis, fatty acid elongation and desaturation, P-450 mediated hydroxylation of drugs and steroid hormones and the PMRS (trans-plasma membrane redox system). CYB5R3 also plays a vital role in mitochondrial respiration. Deficiency of CYB5R3 results in congenital methemoglobinemia.
特点和优势
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外形
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
基本信息
NACRES | NA.41 |
产品性质
生物来源 | rabbit |
质量水平 | 100 |
偶联物 | unconjugated |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
形式 | buffered aqueous solution |
分子量 | antigen 34 kDa |
species reactivity | human |
浓度 | ~1 mg/mL |
technique(s) | ELISA: 1:40000 immunohistochemistry: 1:50-1:100 western blot: 1:500-1:1000 |
NCBI登记号 | P00387 |
UniProt登记号 | P00387 |
运输 | wet ice |
储存温度 | −20℃ |
Gene Information | human ... CYB5R3(1727) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | nwg |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich