Anti-DARC Antibody

产品说明

一般描述

Duffy antigen/chemokine receptor (DARC), also known as Fy glycoprotein (GpFy), is a multi-pass membrane protein belonging to the G-protein coupled receptor Duffy family. DARC binds, with high affinity, several chemokines without transducing any signal, suggesting it may modulate the signals normally induced by these chemokines. DARC is found in adult kidney, adult spleen, bone marrow, and fetal liver. It is expressed along postcapillary venules throughout the body, except in the adult liver.

特异性

This antibody recognizes the C-terminus of DARC.

免疫原

KLH-conjugated linear peptide corresponding to the C-terminus of human DARC.
Epitope: C-terminus

应用

Immunohistochemistry Analysis: 2.5 µg/mL from a representative lot detected DARC in mouse brain tissue.
Research Category
Neuroscience
Research Sub Category
Developmental Neuroscience
Detect Duffy antigen/chemokine receptor using this rabbit polyclonal antibody, Anti-DARC Antibody validated for use in western blotting & IHC (Paraffin).

质量

Evaluated by Western Blotting in mouse brain tissue lysate.

Western Blotting Analysis: 2 µg/mL of this antibody detected DARC in 15 µg of mouse brain tissue lysate.

目标描述

~23 and 35 kDa observed. Uniprot describes two isoforms at ~35 and ~36 kDa

外形

Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
Antigen Affinity Purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

分析说明

Control
Mouse brain tissue lysate

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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