产品说明
一般描述
Dendritic cell-associated lectin-1 (DCAL-1), also known as C-type lectin-like-1 (CLECL1), is a novel C-type lectin-like molecule, encoded by the gene mapped to human chromosome 12p13.31. The encoded protein is exclusively expressed in human hematopoietic cells, in particular at high levels in dendritic cells (DCs) and B cells.
Monoclonal Anti-DCAL-1 (mouse IgM isotype) is derived from the hybridoma UW50 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice, immunized with a human DCAL-1 fusion protein
特异性
Monoclonal Anti-DCAL-1 recognizes human DCAL-1.
免疫原
human DCAL-1 fusion protein.
应用
Monoclonal Anti-DCAL-1 antibody produced in mouse may be used in flow cytometry.
生化/生理作用
Dendritic cell-associated lectin-1 (DCAL-1) functions as a T-cell co-stimulatory molecule and increases interleukin-4 secretion. The encoded protein is also implicated in the regulation of the immune response.
外形
0.01M 磷酸缓冲盐溶液,pH 7.4,含 15mM 叠氮化钠。
储存及稳定性
For continuous use, store at 2-8℃ for up to one month. For extended storage, freeze at -20℃ in working aliquots. Repeated freezing and thawing,or storage in “frost-free” freezers,is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilution samples should be discarded if not used within 12 hours.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
NACRES | NA.41 |
产品性质
生物来源 | mouse |
偶联物 | unconjugated |
抗体形式 | purified from hybridoma cell culture |
antibody product type | primary antibodies |
克隆 | UW50, monoclonal |
形式 | buffered aqueous solution |
species reactivity | human |
浓度 | ~1.0 mg/mL |
technique(s) | flow cytometry: 0.25-0.50 μg/test using 1x106 human Raji cells |
同位素/亚型 | IgM |
UniProt登记号 | Q8IZS7 |
运输 | dry ice |
储存温度 | −20℃ |
Gene Information | human ... CLECL1(160365) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich