产品说明
一般描述
DDAH (Dimethylarginine dimethylaminohydrolase) exists as two isoforms; DDAH1, and DDAH2. Tissues expressing endothelial nitric oxide synthases is predominated by DDAH2.
免疫原
Peptide with sequence SSLCLVLSTRPHS from the C Terminus of the protein sequence according to NP_039268.1.
应用
Anti-DDAH2 antibody produced in goat is suitable for indirect ELISA and western blot applications.
生化/生理作用
DDAH2 (Dimethylarginine dimethylaminohydrolase 2) Activity partly determines the cellular concentration of methylarginine. Concentration of ADMA (asymmetrical dimethylarginine) in endothelial cells is increased on the advent of pharmacological inhibition of DDAH, which also leads to the inhibition of NO-mediated endothelium dependent relaxation of blood vessels.
特点和优势
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外形
Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 质量水平 | 100 |
| 生物来源 | goat |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| species reactivity | mouse, rat, human |
| technique(s) | indirect ELISA: suitable western blot: suitable |
| UniProt登记号 | O95865 |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| Gene Information | human ... DDAH2(23564) |
安全信息
| 象形图 |  |
| 警示用语： | Warning |
| 危险声明 | H315 - H319 |
| 预防措施声明 | P305 + P351 + P338 |
| 危险分类 | Eye Irrit. 2 - Skin Irrit. 2 |
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
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