Anti-DGAT2L4 antibody produced in rabbit

产品说明

一般描述

Diacylglycerol acyl transferases 2 (DGAT2L4) also known as acyl-CoA wax alcohol acyltransferase 2 (AWAT2), is a human multifunctional O-acyltransferase (MFAT). It is commonly expressed in undifferentiated sebocytes. In the human chromosome, the gene is localized on Xq13.1.

免疫原

Synthetic peptide directed towards the C terminal region of human DGAT2L4

生化/生理作用

DGAT2L4 is acyltransferase that predominantly esterify long chain (wax) alcohols with acyl-CoA-derived fatty acids to produce wax esters. Wax esters are enriched in sebum, suggesting that it plays a central role in lipid metabolism in skin. It has no activity using decyl alcohol and significantly prefers the C16 and C18 alcohols. DGAT2L4 may also have 2-acylglycerol O-acyltransferase (MGAT) and acyl-CoA:retinol acyltransferase (ARAT) activities, to catalyze the synthesis of diacylglycerols and retinyl esters, however this activity is unclear in vivo.

序列

Synthetic peptide located within the following region: GEPLPMPKIENPSQEIVAKYHTLYIDALRKLFDQHKTKFGISETQELEII

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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