产品说明
一般描述
Doublesex- and mab-3-related transcription factor 2 is encoded by the DMRT2 gene in human and directly regulates early activation of the myogenic determination gene MYF5 by binding in a sequence-specific manner to its early epaxial enhancer element. In addition, it is also involved in somite develoment during embryogenesis. The human protein shares a DM DNA-binding domain with Drosophila ′doublesex′ (dsx) and C. elegans mab3 gene products involved in sex determination.
免疫原
KLH-conjugated linear peptide corresponding to human DMRT2.
应用
Research Sub Category
Nuclear Receptors
Anti-DMRT2 Antibody is an antibody against DMRT2 for use in Western Blotting and Immunohistochemistry.
Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected DMRT2 in human kidney and rat testis tissue.
Research Category
Epigenetics & Nuclear Function
质量
Evaluated by Western Blotting in human kidney tissue lysate.
Western Blotting Analysis: 0.25 µg/mL of this antibody detected DMRT2 in 10 µg of human kidney tissue lysate.
目标描述
~70 kDa observed
外形
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Affinity purified
储存及稳定性
Stable for 1 year at 2-8°C from date of receipt.
其他说明
Concentration: Please refer to lot specific datasheet.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
产品性质
生物来源 | rabbit |
质量水平 | 100 |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
纯化方式 | affinity chromatography |
species reactivity | human, rat |
technique(s) | immunohistochemistry: suitable western blot: suitable |
NCBI登记号 | NP_870987 |
UniProt登记号 | Q9Y5R5 |
运输 | wet ice |
Gene Information | human ... DMRT2(10655) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich