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Anti-DNA polymerase δ p125 antibody, Rat monoclonal

品牌
Sigma-Aldrich
货号
SAB4200053
规格纯度
clone PDG 5G1, purified from hybridoma cell culture
参考价格
7601.62 *本价格含增值税费
促销
服务
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  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-DNA polymerase δ p125 antibody, Rat monoclonal
Anti-Polymerase (DNA directed), delta 1, catalytic subunit 125kDa
Anti-POLD1
Monoclonal Anti-DNA polymerase δ p125 antibody produced in rat
产品介绍:

产品说明

一般描述

Monoclonal Anti-DNA polymerase d p125 (rat IgG2a isotype) is derived from the hybridoma PDG 5G1 produced by the fusion of mouse myeloma cells (P3X63Ag8.653) and splenocytes from rat immunized with human p125. The catalytic subunit p125 (POLD1), which is encoded by the Pold1 gene, is highly conserved among eukaryotes. Pold1 comprises of two primary functional domains: an exonuclease domain near the N-terminus and the subsequent polymerase domain.

免疫原

human p125

应用

Monoclonal Anti-DNA polymerase δ p125 antibody produced in rat has been used in:

  • immunoblotting
  • immunoprecipitation
  • immunocytochemistry
  • co-immunoprecipitation

生化/生理作用

The exonuclease domain of the catalytic subunit p125 (POLD1) has the ability to catalyze 3′−5′ exonucleolytic proofreading and the polymerase domain helps to catalyze DNA synthesis. Mutations in this subunit have been implicated in mammalian embryogenesis and tumorigenesis.

外形

Solution in 0.01M phosphate buffered saline pH 7.4, containing 15 mM sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRESNA.41

产品性质

质量水平200
生物来源rat
抗体形式purified from hybridoma cell culture
antibody product typeprimary antibodies
克隆PDG 5G1, monoclonal
形式buffered aqueous solution
分子量antigen ~125 kDa
species reactivityhuman, mouse, rat
包装antibody small pack of 25 μL
technique(s)immunocytochemistry: suitable
immunoprecipitation (IP): suitable
western blot: 0.5-1.0 μg/mL using Jurkat cells extract
UniProt登记号P28340
运输dry ice
储存温度−20℃
Gene Informationhuman ... POLD1(5424)

安全信息

储存分类代码12 - Non Combustible Liquids
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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