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Anti-EFTUD2 antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB4503626
规格纯度
affinity isolated antibody
参考价格
5045.46 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-EFTUD2 antibody produced in rabbit
U5 snRNP- specific protein
SNRP116
116 kDa U5 small nuclear ribonucleoprotein component
KIAA0031
116 kDa
产品介绍:

产品说明

一般描述

Anti-EFTUD2 Antibody detects endogenous levels of total EFTUD2 protein.
EFTUD2 (Elongation factor Tu GTP binding domain containing 2) is a member of the U5 small nuclear ribonucleoprotein particle (snRNP) located on chromosome region 17q21.31. It encodes a small GTPase (116kDa) component of the major spliceosome. It consists of a GTP-binding domain and several other conserved domains homologous to the translational elongation factor EF-2. Its N-terminal domain has an acidic domain.

免疫原

The antiserum was produced against synthesized peptide derived from human EFTUD2.

Immunogen Range: 321-370

应用

Anti-EFTUD2 antibody produced in rabbit is suitable for immunohistochemistry and western blot.

生化/生理作用

EFTUD2 (Elongation factor Tu GTP binding domain containing 2) acts as a component of the spliceosome complex during translocation of mRNA on the ribosome. It produces mature mRNAs by binding to GTP during the processing of precursor mRNAs. Haploinsufficient genetic mutation in EFTUD2 causes a sporadic malformation syndrome, mandibulofacial dysostosis with microcephaly (MFDM), characterized with severe craniofacial abnormalities, microcephaly, growth delay, hearing loss, cleft palate, choanal atresia and dysmorphic features.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外形

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

基本信息

NACRESNA.41

产品性质

生物来源rabbit
质量水平100
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量antigen 109 kDa
species reactivityhuman, mouse
浓度~1 mg/mL
technique(s)ELISA: 1:40000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI登记号Q15029
UniProt登记号Q15029
运输wet ice
储存温度−20℃
Gene Informationhuman ... EFTUD2(9343)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKnwg
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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