产品说明
一般描述
The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5′ end of messenger RNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the 5′-cap structure. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. This gene acts as a proto-oncogene, and its expression and activation is associated with transformation and tumorigenesis. Several pseudogenes of this gene are found on other chromosomes. Alternative splicing results in multiple transcript variants.
免疫原
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human EIF4E (NP_001959.1).
外形
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
储存及稳定性
Store at -20℃. Avoid freeze / thaw cycles.
产品性质
生物来源 | rabbit |
质量水平 | 100 |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
形式 | buffered aqueous solution |
分子量 | 25 27 28 |
species reactivity | human, mouse, rat |
浓度 | 1.85 mg/ml |
technique(s) | immunofluorescence: 1:50-1:200 immunohistochemistry: 1:50-1:100 immunoprecipitation (IP): 1:50-1:100 western blot: 1:500-1:2000 |
UniProt登记号 | P06730 |
运输 | wet ice |
储存温度 | −20℃ |
Gene Information | human ... EIF4E(1977) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich