产品说明
一般描述
Eukaryotic translation initiation factor 4E family member 3 (EIF4E3) is a member of the eukaryotic translation initiation factor 4E (eIF4E) family involved in the initiation of mRNA translation by binding to its 5′-prime cap structure and targeting the mRNA to the ribosome.
特异性
Anti-EIF4E3 polyclonal antibody reacts with chicken, human, mouse, rat, bovine, and zebrafish eukaryotic translation initiation factor 4E family member 3 proteins.
免疫原
Synthetic peptide directed towards the middle region of human EIF4E3
应用
Anti-EIF4E3 polyclonal antibody is used to tag eukaryotic translation initiation factor 4E family member 3 proteins for detection and quantitation by Western blotting and in cells and tissues by immunohistochemical (IHC) techniques. It is used as a probe to study the role of eukaryotic translation initiation factor 4E family member 3 in the initiation of mRNA translation.
生化/生理作用
EIF4E3 belongs to the EIF4E family of translational initiation factors that interact with the 5-prime cap structure of mRNA and recruit mRNA to the ribosome.
序列
Synthetic peptide located within the following region: VQVWNVNASLVGEATVLEKIYELLPHITFKAVFYKPHEEHHAFEGGRGKH
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
NACRES | NA.41 |
产品性质
生物来源 | rabbit |
质量水平 | 100 |
偶联物 | unconjugated |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
形式 | buffered aqueous solution |
分子量 | 24 kDa |
species reactivity | horse, dog, guinea pig, rabbit, rat, mouse, bovine, human |
浓度 | 0.5 mg - 1 mg/mL |
technique(s) | western blot: suitable |
NCBI登记号 | NP_001128121 |
UniProt登记号 | Q8N5X7 |
运输 | wet ice |
储存温度 | −20℃ |
Gene Information | human ... EIF4E3(317649) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich