Anti-FABP1 Antibody

产品说明

一般描述

FABP1, also known as Fatty acid-binding protein, Liver Fatty acid-binding protein, Fatty acid-binding protein 1, Liver-type fatty acid-binding protein, L-FABP, Squalene- and sterol-carrier protein, SCP, Z-protein, or p14, and encoded by the gene FABP1/FABPL, is an important fatty acid binding and transport protein. FABP1 is produced in the liver and is part of a family of lipid carrier proteins. FABP1 facilitate the transfer of fatty acids between extra and intracellular membranes. FABP1 level in the blood is used as a biomarker for obesity and type II diabetes. Additionally, recent research indicates that FABP1 can modulate stellate cell activation and this may lead to diet-induced nonalcoholic fatty liver disease, thus FABP1 is a key focus of metabolic research.

特异性

Other homologies: Mouse (94% sequence homology).

免疫原

Epitope: Near N-terminus
KLH-conjugated linear peptide corresponding to human FABP1 near the N-terminus.

应用

This Anti-FABP1 Antibody is validated for use in Western Blotting and Immunohistochemistry for the detection of FABP1.
Research Sub Category
Apoptosis - Additional
Immunohistochemistry Analysis: A 1:2,000 dilution from a representative lot detected FABP1 in rat liver tissue.
Research Category
Apoptosis & Cancer

质量

Evaluated by Western Blotting in HepG2 cell lysate.

Western Blotting Analysis: 2.0 µg/mL of this antibody detected FABP1 in 10 µg of HepG2 cell lysate.

目标描述

~14 kDa observed

外形

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Affinity purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

其他说明

Concentration: Please refer to lot specific datasheet.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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