产品说明
一般描述
Fc fragment of IgG receptor Ia (FCGR1A) gene encodes a protein that plays an important role in the immune response. This protein is a high-affinity Fc-gamma receptor. The gene is one of three related gene family members located on chromosome 1. (provided by RefSeq). Fc fragment of IgG receptor Ia (FCGR1A) gene is located on human chromosome 1q21.2. FCGR1A is expressed on monocytes and macrophages.
免疫原
FCGR1A (NP_000557.1, 1 a.a. ~ 374 a.a) full-length human protein.
Sequence
MWFLTTLLLWVPVDGQVDTTKAVITLQPPWVSVFQEETVTLHCEVLHLPGSSSTQWFLNGTATQTSTPSYRITSASVNDSGEYRCQRGLSGRSDPIQLEIHRGWLLLQVSSRVFTEGEPLALRCHAWKDKLVYNVLYYRNGKAFKFFHWNSNLTILKTNISHNGTYHCSGMGKHRYTSAGISVTVKELFPAPVLNASVTSPLLEGNLVTLSCETKLLLQRPGLQLYFSFYMGSKTLRGRNTSSEYQILTARREDSGLYWCEAATEDGNVLKRSPELELQVLGLQLPTPVWFHVLFYLAVGIMFLVNTVLWVTIRKELKRKKKWDLEISLDSGHEKKVISSLQEDRHLEEELKCQEQKEEQLQEGVHRKEPQGAT
生化/生理作用
Fc fragment of IgG receptor Ia (FCGR1A) functions as the single high-affinity receptor of immunoglobulin G (IgG) in humans. It also regulates immune inflammation. FCGR1A acts as a diagnostic marker for bacterial infections, such as neonatal sepsis. FCGR1A is an important biomarker for rheumatoid arthritis (RA).
外形
Solution in phosphate buffered saline, pH 7.4
基本信息
| NACRES | NA.41 |
产品性质
| 质量水平 | 100 |
| 生物来源 | mouse |
| 偶联物 | unconjugated |
| 抗体形式 | purified immunoglobulin |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | antigen ~42.6 kDa |
| species reactivity | human |
| technique(s) | western blot: 1 μg/mL |
| NCBI登记号 | NM_000566.2 |
| UniProt登记号 | P12314 |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| Gene Information | human ... FCGR1A(2209) |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
