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位置:首页 > 品牌 > Sigma-Aldrich > Anti-FYVE Antibody, clone 7F11.1

Anti-FYVE Antibody, clone 7F11.1

品牌
Sigma-Aldrich
货号
MABC195
规格纯度
clone 7F11.1, from mouse
参考价格
5854.74 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-FYVE Antibody, clone 7F11.1
Zinc finger FYVE domain-containing protein 26, FYVE domain-containing centrosomal protein, FYVE-CENT, Spastizin, FYVE
产品介绍:

产品说明

一般描述

FYVE, also known as Zinc finger FYVE domain-containing protein 26, or FYVE domain-containing centrosomal protein (FYVE-CENT), or Spastizin, and encoded by the gene ZFYVE26/KIAA0321, is a phosphosphatidylinositol 3-phosphate-binding protein required for the abscission step in cytokinesis. FYVE is recruited to the midbody during cytokinesis and acts as a regulator of abscission. FYVE also be required for efficient homologous recombination DNA double-strand break repair. FYVE is cytoskeleton associated and localized in the cytoplasm in resting cells but at the centrosome during cell division. FYVE is expressed in all cells and tissues. Defects in FYVE may be associated with Spastic paraplegia 15, a form of spastic paraplegia, a neurodegenerative disorder characterized by a slow, gradual, progressive weakness and spasticity of the lower limbs.

免疫原

GST-tagged recombinant protein corresponding to human FYVE.

应用

Anti-FYVE Antibody, clone 7F11.1 detects level of FYVE & has been published & validated for use in FYVE.
Research Sub Category
Apoptosis - Additional
Research Category
Apoptosis & Cancer
Immunohistochemisty Analysis: A 1:50 dilution from a representative lot detected FYVE in human frontal cortex and thalamus tissues.

质量

Evaluated by Immunohistochemistry in human cerebellum tissue.

Immunohistochemisty Analysis: A 1:50 dilution from a representative lot detected FYVE in human cerebellum tissue.

目标描述

~285 kDa calculated. Four isoforms are known to exist at 285 kDa (isoform 1), 283 kDa (isoform 2), 78 kDa (isoform 3), and 89 kDa (isoform 4).

外形

Format: Purified
Purified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Protein G Purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss32160702
NACRESNA.41

产品性质

质量水平100
生物来源mouse
抗体形式purified immunoglobulin
antibody product typeprimary antibodies
克隆7F11.1, monoclonal
species reactivityhuman
technique(s)immunohistochemistry: suitable (paraffin)
同位素/亚型IgG2aκ
NCBI登记号NP_056161
UniProt登记号Q68DK2
运输wet ice
Gene Informationhuman ... ZFYVE26(23503)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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