Anti-GABA(A)R BETA 1 Protein Antibody, clone N96/55

产品说明

一般描述

GABA(A)R, beta-1 is a subunit of the GABA receptor. GABA receptors belong to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid or GABA is the major inhibitory neurotransmitter in the vertebrate brain. GABA mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho. GABA receptors play an important role in transmembrane ion transport, excitability and synaptic transmission.

特异性

Other homologies: Human (95% sequence homology).
This antibody does not cross react with GABA-A-R, Beta 2 Protein or GABA-A-R, Beta 3 Protein.

免疫原

Fusion protein corresponding to mouse GABA(A)R, BETA 1.

应用

Research Sub Category
Signaling Neuroscience
Immunohistochemistry Analysis: A 1:500 dilution from a representative lot detected GABA(A)R, BETA 1 Protein in rat olfactory lobe tissue.

Western Blot Analysis: A representative lot detected GABA(A)R, BETA 1 Protein in rat brain membrane tissue lysate.

Immunohistochemistry Analysis: A representative lot detected GABA(A)R, BETA 1 Protein in rat hippocampus tissue.
Research Category
Neuroscience
This GABA(A)R antibody is validated for use in IHC & WB for the detection of the GABA(A)R protein.

质量

Evaluated by Immunohistochemistry in rat hippocampus tissue.

Immunohistochemistry Analysis: A 1:500 dilution from a representative lot detected GABA(A)R, BETA 1 Protein in rat hippocampus tissue.

目标描述

~55 kDa observed

外形

Format: Purified
Purified monoclonal mouse IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Protein G Purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

分析说明

Control
Rat hippocampus tissue

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

产品性质

安全信息