Anti-GATA4 antibody produced in rabbit

产品说明

一般描述

The GATA zinc finger transcription factors are characterized by their ability to bind to the promoter region DNA sequence "GATA" within various genes. GATA4, prevalent in endoderm-derived organs, regulates various genes involved in embryogenesis and in myocardial differentiation and function.

特异性

Anti-GATA4 polyclonal antibody reacts with human, mouse, rat, pig, and canine GATA4 transcription factors.

免疫原

Synthetic peptide directed towards the N terminal region of human GATA4

应用

Anti-GATA4 polyclonal antibody is used to tag GATA4 proteins for detection and quantitation by Western blotting and in cells and tissues by immunohistochemical (IHC) techniques. It is used as a probe to study the possible roles of GATA4 in the regulation of embryogenesis and differentiation primarily within endoderm-derived organs and tissues.

生化/生理作用

GATA4 is a member of the GATA family of zinc-finger transcription factors. Members of this family recognize the GATA motif which is present in the promoters of many genes. GATA4is thought to regulate genes involved in embryogenesis and in myocardial differentiation and function. Mutations in this gene have been associated with cardiac septal defects.This gene encodes a member of the GATA family of zinc-finger transcription factors. Members of this family recognize the GATA motif which is present in the promoters of many genes. This protein is thought to regulate genes involved in embryogenesis and in myocardial differentiation and function. Mutations in this gene have been associated with cardiac septal defects.

序列

Synthetic peptide located within the following region: MYQSLAMAANHGPPPGAYEAGGPGAFMHGAGAASSPVYVPTPRVPSSVLG

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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