Anti-GIP antibody produced in rabbit

产品说明

一般描述

Glucose-dependent insulinotropic polypeptide (GIP) or gastric inhibitory polypeptide is a 42-amino acid gastrointestinal regulatory peptide, expressed in K cells of the small intestine and in cells of the submandibular salivary gland. The gene encoding GIP is localized on human chromosome 17.

特异性

The antibody detects endogenous levels of total GIP protein.

免疫原

Fusion protein corresponding to a region derived from internal residues of human gastric inhibitory polypeptide

生化/生理作用

In the presence of glucose, glucose-dependent insulinotropic polypeptide (GIP) induces insulin secretion. It acts as an antagonist of the human GIP receptor. Aberrations in GIP are associated with visceral fat accumulation. The protein has been studied to have a protective function in obesity and atherosclerosis.

特点和优势

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外形

Rabbit IgG in pH7.3 PBS, 0.05% NaN₃, 50% Glycerol.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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