产品说明
一般描述
AMPA receptors mediate fast synaptic current at most excitatory synapses, with stoichiometry characterized by subtype composition.There are four types of AMPA selective GluR subunits (GluR1, GluR2, GluR3 and GluR4). Tetrameric or pentameric combinations of different subunits contributes to the functional diversity of AMPA receptors. The insertion or removal of GluR1/GluR4 oligomeric channels from postsynaptic membranes appears to be LTP/LTD activity dependent while GluR2/GluR3 oligomers are continuously cycling. Millipore’s anti-GluR2/3 antibody is useful for localizing expression of GluR2/GluR3 receptor assemblies in the PSD.
特异性
Reacts with Glutamate Receptor 3 (GluR3). No cross reactivity with GluR2.
免疫原
Fusion protein, N-terminus of GluR3
应用
Immunohistochemistry: A previous lot of this antibody was used in IH.
Optimal working dilutions must be determined by end user.
Anti-Glutamate Receptor 3 Antibody, clone 3B3 is an antibody against Glutamate Receptor 3 for use in WB, IC, IH, IH(P).
质量
Western Blot Analysis: A previous lot of this antibody was used in WB.
目标描述
~ 110 kDa
外形
Liquid in PBS. Contains no preservative.
Format: Purified
Protein A purified
分析说明
Control
Brain
Hippocampal tissue
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
产品性质
质量水平 | 100 |
生物来源 | mouse |
抗体形式 | purified antibody |
antibody product type | primary antibodies |
克隆 | 3B3, monoclonal |
species reactivity | monkey, mouse, human |
species reactivity (predicted by homology) | rat |
manufacturer/tradename | Chemicon® |
technique(s) | immunocytochemistry: suitable immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable western blot: suitable |
同位素/亚型 | IgG1κ |
NCBI登记号 | NM_000840.2 |
UniProt登记号 | P42263 |
运输 | dry ice |
Gene Information | human ... GRIA3(2892) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 2 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich