Anti-GPR15 antibody produced in rabbit

产品说明

一般描述

GPR15 (G-protein–coupled receptor 15) is a membrane-localizing protein or a novel G-protein–coupled receptor, located on human chromosome 3. It is also called as brother of Bonzo (BOB). GPR15 is expressed in the lymphoid tissue, colon and Th2 cells.

免疫原

GPR15 antibody was raised against a peptide corresponding to amino acids near the amino terminus of human GPR15. The sequence differs from those of African green monkey and pig-tailed macaque BOB by one amino acid (2).

生化/生理作用

GPR15 (G-protein–coupled receptor 15) controls T-cell migration and immunity. It acts as an alternative coreceptor for HIV and Simian immunodeficiency virus. GPR15 participates in lymphocyte homing in the large intestine. It also plays a major role in the progression of inflammation in the colon. GPR15 helps in the trafficking of dendritic epidermal T cells to the epidermal tissues.

特点和优势

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联系

The action of this antibody can be blocked using blocking peptide SBP3500260.

外形

Supplied in PBS with 0.02% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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