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Anti-GST·Tag fusion protein Antibody

品牌
Sigma-Aldrich
货号
MAC111
规格纯度
clone 8-326.6.1, from mouse
参考价格
3516.39 *本价格含增值税费
促销
服务
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数量
-+
产品名称:
Anti-GST·Tag fusion protein Antibody
Glutathione S-transferase class-mu 26 kDa isozyme, GST 26, Sj26 antigen, SjGST
产品介绍:

产品说明

一般描述

GST (glutathione-S-transferase) represents a major group of detoxification enzymes, which are known to exist as multiple cytosolic and membrane-bound isoenzymes, with distinct catalytic and noncatalytic binding properties. Whereas the cytosolic enzymes are encoded by at least five distantly related gene families, the membrane-bound enzymes are encoded by single genes. GST is regulated and induced by a diverse range of xenobiotics. Many, but not all, inducers of GST, act through either the antioxidant-responsive element (ARE), the GST P enhancer 1(GPE), the xenobiotic-responsive element (XRE), or the glucocorticoid-responsive element (GRE). Barbiturates may transcriptionally activate GST through a Barbie box element. Many of the compounds that induce GST are also GST substrates, or are metabolized by cytochrome P-450 monooxygenases into compounds that can serve as GST substrates. Because the expression levels of GST play a critical role in determining the sensitivity of cells to a broad range of toxic chemicals, GST is suggested to contribute to resistance against carcinogens, antitumor drugs, environmental pollutants, and products of oxidative stress.

免疫原

Gluththione-S-transferase (GST) domain from Schistosoma Japonicum

应用

This Anti-GST•Tag fusion protein Antibody is validated for use in Western Blotting, ICC, Immunoprecipitation, ELISA for the detection of GST•Tag fusion protein.
Research Category
Epitope Tags & General Use
Research Sub Category
Epitope Tags
Immunocytochemistry Analysis: A representative lot detected GST•Tag fusion protein in transfected COS-1 cells.

Immunoprecipitation Analysis: A representative lot immunoprecipitated GST•Tag fusion protein sequence in IP.

ELISA Analysis: A representative lot detected GST•Tag protein sequence in ELISA.

质量

Evaluated by Western Blot in Posi-Tag Epitope Tag Control.

Western Blot Analysis: This antibody detected GST•Tag fusion protein in 5 µL of Posi-Tag Epitope Tag Control.

目标描述

~45 kDa observed. The molecular weight of the GST•Tag fusion protein is not ~45 kDa The Posi-Tag Epitope Tag Control, which contains the fusion protein, is observed at ~45 kDa in Western Blot.

外形

Purified mouse monoclonal IgG1κ cultured supernatant in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Format: Purified
Protein G Purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

分析说明

Control
Posi-Tag Epitope Tag Control

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss32160702
NACRESNA.41

产品性质

质量水平100
生物来源mouse
抗体形式purified immunoglobulin
克隆8-326.6.1, monoclonal
species reactivity (predicted by homology)all
technique(s)ELISA: suitable
immunocytochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
同位素/亚型IgG1κ
UniProt登记号P08515
运输wet ice

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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