产品说明
一般描述
Human equilibrative nucleoside transporter 1 (hENT1) is a member of the equilibrative nucleoside transporter family. It is a transmembrane glycoprotein that localizes to the plasma and mitochondrial membranes and mediates the cellular uptake of nucleosides from the surrounding medium. The protein is sensitive to inhibition by nitrobenzylthioinosine (NBMPR). It is considered as a drug carrier. Nucleoside transporters such as hENT1 are required for nucleotide synthesis in cells that lack de novo nucleoside synthesis pathways, and are also necessary for the uptake of cytotoxic nucleosides used for cancer and viral chemotherapies.
免疫原
Synthetic peptide derived from the internal region of human hENT1 protein.
特点和优势
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外形
0.1 ml rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
NACRES | NA.41 |
产品性质
生物来源 | rabbit |
质量水平 | 100 |
重组 | expressed in proprietary host |
偶联物 | unconjugated |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | SP120, monoclonal |
species reactivity | human (tested) |
species reactivity (predicted by homology) | rabbit, rat |
technique(s) | immunohistochemistry: 1:100 |
同位素/亚型 | IgG |
UniProt登记号 | Q99808 |
运输 | wet ice |
储存温度 | 2-8℃ |
Gene Information | human ... SLC29A1(2030) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 2 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich